Liver from bone marrow in humans

  title={Liver from bone marrow in humans},
  author={N. Theise and M. Nimmakayalu and R. Gardner and P. Illei and G. Morgan and L. Teperman and O. Henegariu and D. Krause},
  • N. Theise, M. Nimmakayalu, +5 authors D. Krause
  • Published 2000
  • Biology, Medicine
  • Hepatology
  • It has been shown in animal models that hepatocytes and cholangiocytes can derive from bone marrow cells. We have investigated whether such a process occurs in humans. Archival autopsy and biopsy liver specimens were obtained from 2 female recipients of therapeutic bone marrow transplantations with male donors and from 4 male recipients of orthotopic liver transplantations from female donors. Immunohistochemical staining with monoclonal antibody CAM5.2, specific for cytokeratins 8, 18, and 19… CONTINUE READING
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