Liver fluke‐associated cholangiocarcinoma

  title={Liver fluke‐associated cholangiocarcinoma},
  author={Prasit Watanapa and Wattana B Watanapa},
  journal={British Journal of Surgery},
Infection with liver flukes has been reported to be associated with bile duct malignancy. 

Lung and liver flukes

The immune response to Paragonimus westermani infection is marked by an up-regulation in the immune-compulsive response to Fasciola hepatica, and the immune defences of the immune system are disturbed.

Helicobacter bilis colonization of the biliary system in patients with pancreaticobiliary maljunction

This study investigated the prevalence of H. bilis colonization of the biliary system of patients with pancreaticobiliary maljunction and found that it was high in patients with PBM.

Diagnosis efficacy of CEUS for hepatic inflammatory lesions

In this study, the efficacy of US/CEUS and clinicopathologic parameters in differential diagnosis of hepatic inflammatory lesions were evaluated and the results confirmed the importance of knowing the carrier and removal status of canine coronavirus.

Cholangiocarcinoma in USA‐ versus Asian‐born Asians: Is viral hepatitis a factor?

This study attempted to clarify the risk factor profile for immigrant Asians compared with the USA population, and found liver and biliary tract cancers are more common in Asian countries than in the USA.

Epidemiology and Pathogenesis of Cholangiocarcinoma

This chapter summarises the major reported epidemiological changes and describes the major known risk factors as well as the molecular pathogenesis of cholangiocarcinoma.

Endoscopic Evaluation and Management of Cholangiocarcinoma.

간흡충증(Clonorchis Sinensis Infestation)과 담도암(Cholangiocellular Carcinoma): Etiologic Relationship

ᆞHepatolithiasis ᆞOpisthorchis viverrini infestation, primary sclerosing cholangitis, and anomalous union of pancreaticobiliary junction.

Expression of stage-specific Fasciola proteases and their evaluation in vaccination trials

The liver flukes Fasciola hepatica and F. gigantica cause infectious disease in ruminants and humans and the geographical range of these two parasite species ensures that infection can occur worldwide.

Diagnosis and Management of Intrahepatic and Extrahepatic Cholangiocarcinoma.

In this chapter, the risk factors, clinical presentation, and management of cholangiocarcinoma are reviewed.

Malignant Transformation Arising Within Unusual and Rare Hepatic Lesions: Fibropolycystic Disease Form of Ductal Plate Malformation and Biliary Adenofibroma

2 cases of intrahepatic cholangiocarcinoma arising within unusual and rare hepatic lesions, fibropolycystic liver disease form of ductal plate malformation and biliary adenofibroma, whose association with malignancy is rarely reported in the literature are described.



Liver-fluke infection as an aetiological factor in bile-duct carcinoma of man.

  • D. Flavell
  • Medicine
    Transactions of the Royal Society of Tropical Medicine and Hygiene
  • 1981


Summary The persistence of Clonorchis sinensis infestation of the bile duct for a period of at least 26 years without neoplasia supervening is reported in a Chinese immigrant to Australia.

Pathology and immunology of Clonorchis sinensis infection of the liver.

  • T. Sun
  • Medicine
    Annals of clinical and laboratory science
  • 1984
The existence of clonorchiasis cases among the Asian immigrants and the major clinical and pathologic features encountered in those patients is emphasized and the specific immunologic phenomenon in clonOrchiasis is described.

Cholangiocarcinoma in patients with opisthorchiasis

Survival after surgical treatment of cholangiocarcinoma in patients with opisthorchiasis is broadly similar to that reported for cholangsiocARCinoma without liver fluke infestation.

The role of infection by opisthorchis viverrini, hepatitis B virus, and aflatoxin exposure in the etiology of liver cancer in thailand. A correlation study

There was little geographic variation in incidence of hepatocellular carcinoma or in prevalence of the major risk factors (chronic carriage of hepatitis B virus and exposure to aflatoxin), and apparently there was little relationship between them.

Liver changes in hamsters infected with a liver fluke of man, Opisthorchis viverrini.

Findings suggest that immunopathologic mechanisms may be important in the pathogenesis of liver fluke disease.

Liver cancer in Thailand. I. A case‐control study of cholangiocarcinoma

The results suggest that males may be at higher risk than females for cholangiocarcinoma, and regular users of betel nut had a high risk, a possible mechanism being through their increased exposure to nitro‐samines.

Generation of High Yields of Syrian Hamster Cholangiocellular Carcinomas and Hepatocellular Nodules by Combined Nitrite and Aminopyrine Administration and Opisthorchis viverrini Infection

The results indicate that parasite associated liver injury and non‐specific compensatory regeneration may play an important role in generation of both hepatocellular and cholangiocellular carcinomas in man.