Liver fibrosis.

  title={Liver fibrosis.},
  author={Ram{\'o}n Bataller and David Brenner},
  journal={The Journal of clinical investigation},
  volume={115 2},
Liver fibrosis is the excessive accumulation of extracellular matrix proteins including collagen that occurs in most types of chronic liver diseases. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension and often requires liver transplantation. Our knowledge of the cellular and molecular mechanisms of liver fibrosis has greatly advanced. Activated hepatic stellate cells, portal fibroblasts, and myofibroblasts of bone marrow origin have been identified as major… CONTINUE READING
Highly Influential
This paper has highly influenced 129 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
1,400 Citations
129 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 1,400 extracted citations


Publications referenced by this paper.
Showing 1-10 of 129 references

The potential role of genes in nonalcoholic fatty liver disease

  • C. P. Day
  • Clin. Liver Dis. 8:673–691,
  • 2004
Highly Influential
12 Excerpts

Conditional tetracyclineregulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis

  • E Ueberham
  • Hepatology .
  • 2003
Highly Influential
9 Excerpts

Similar Papers

Loading similar papers…