Liver fibrosis.

@article{Bataller2005LiverF,
  title={Liver fibrosis.},
  author={Ram{\'o}n Bataller and David Brenner},
  journal={The Journal of clinical investigation},
  year={2005},
  volume={115 2},
  pages={209-18}
}
Liver fibrosis is the excessive accumulation of extracellular matrix proteins including collagen that occurs in most types of chronic liver diseases. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension and often requires liver transplantation. Our knowledge of the cellular and molecular mechanisms of liver fibrosis has greatly advanced. Activated hepatic stellate cells, portal fibroblasts, and myofibroblasts of bone marrow origin have been identified as major… CONTINUE READING
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