Liver fibrosis protects mice from acute hepatocellular injury.

@article{Bourbonnais2012LiverFP,
  title={Liver fibrosis protects mice from acute hepatocellular injury.},
  author={Eric Bourbonnais and Val{\'e}rie-Ann Raymond and Chantal Ethier and Bich Ngoc Thi Nguyen and Marc Saba El-Leil and Sylvain Meloche and Marc Bilodeau},
  journal={Gastroenterology},
  year={2012},
  volume={142 1},
  pages={130-139.e4}
}
BACKGROUND & AIMS Development of fibrosis is part of the pathophysiologic process of chronic liver disease. Although it is considered deleterious, it also represents a form of tissue repair. Deposition of extracellular matrix changes the cellular environment of the liver; we investigated whether it increases resistance to noxious stimuli and the role of changes in intracellular signaling to hepatocytes in mediating this effect. METHODS Primary cultures of mouse hepatocytes were exposed to… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.

Similar Papers

Loading similar papers…