Liver fibrosis: an intravoxel incoherent motion (IVIM) study.

  title={Liver fibrosis: an intravoxel incoherent motion (IVIM) study.},
  author={April M. Chow and Darwin S. Gao and Shu Juan Fan and Zhongwei Qiao and Frank Y.F. Lee and Jian Yang and Kwan Man and Ed Xuekui Wu},
  journal={Journal of magnetic resonance imaging : JMRI},
  volume={36 1},
PURPOSE To characterize longitudinal changes in molecular water diffusion, blood microcirculation, and their contributions to the apparent diffusion changes using intravoxel incoherent motion (IVIM) analysis in an experimental mouse model of liver fibrosis. MATERIALS AND METHODS Liver fibrosis was induced in male adult C57BL/6N mice (22-25 g; n = 12) by repetitive dosing of carbon tetrachloride (CCl(4) ). The respiratory-gated diffusion-weighted (DW) images were acquired using single-shot… CONTINUE READING