Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome.

  title={Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome.},
  author={J E Kaslow and L. Graham Rucker and Rie Onishi},
  journal={Archives of internal medicine},
  volume={149 11},
Chronic fatigue syndrome is a recently defined entity for which clinical criteria were proposed by the Centers for Disease Control, Atlanta, Ga. A frequently advocated treatment in Southern California is an injectable solution of bovine liver extract containing folic acid and cyanocobalamin (LEFAC). We conducted a double-blind, placebo-controlled, crossover trial of intramuscular LEFAC in 15 patients who met the Centers for Disease Control criteria for chronic fatigue syndrome. Although… CONTINUE READING
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