Liver disease: Kupffer cells regulate the progression of ALD and NAFLD

@article{Smith2013LiverDK,
  title={Liver disease: Kupffer cells regulate the progression of ALD and NAFLD},
  author={Katherine N. Smith},
  journal={Nature Reviews Gastroenterology &Hepatology},
  year={2013},
  volume={10},
  pages={503-503}
}
The researchers found that patients who are morbidly obese or those who are heavy alcohol drinkers, but who have little hepatic injury and steatosis, have higher expression levels of M2 Kupffer cell genes than patients who have more extensive liver lesions (including hepatocyte steatosis and fibrogenesis). Data from mouse models of ALD and NAFLD supported these findings from patients. Mice that are resistant to the effects of alcohol or a high-fat diet had a high M2:M1 Kupffer cell ratio. By… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…