Liver cell proliferation induced by nafenopin and cyproterone acetate is not associated with increases in activation of transcription factors NF-kappaB and AP-1 or with expression of tumor necrosis factor alpha.

@article{Menegazzi1997LiverCP,
  title={Liver cell proliferation induced by nafenopin and cyproterone acetate is not associated with increases in activation of transcription factors NF-kappaB and AP-1 or with expression of tumor necrosis factor alpha.},
  author={Marta Menegazzi and A Carcereri-De Prati and Hiroshi Suzuki and Hishashi Shinozuka and Monica Pibiri and Rosaria Piga and Amedeo Columbano and Giovanna Maria Ledda-Columbano},
  journal={Hepatology},
  year={1997},
  volume={25 3},
  pages={585-92}
}
Our previous studies have shown a different pattern of immediate early gene and growth factor gene expression between compensatory liver regeneration occurring after cell loss/death and direct hyperplasia induced by primary mitogens. In the present study, modifications in the activation of two transcription factors, NF-kappaB and AP-1; steady-state levels of tumor necrosis factor alpha (TNF-alpha) messenger RNA (mRNA); and induction of the inducible nitric oxide synthase (iNOS) were examined in… CONTINUE READING