Liver cancer: neonatal estrogen enhances induction by a carcinogen.

Abstract

A single injection of 100 micrograms of estradiol benzoate into newborn rats was followed after weaning by dietary treatment with one of two dosages of the carcinogen N-hydroxy-N-2-fluorenylacetamide. Autopsies 26 weeks later showed a higher incidence of liver cancer in male and, particularly, female rats injected with hormone than in controls. The weights… (More)

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Cite this paper

@article{WEISBURGER1966LiverCN, title={Liver cancer: neonatal estrogen enhances induction by a carcinogen.}, author={JOHNH. WEISBURGER and Reiko Yamamoto and J. Korzis and Elizabeth K. Weisburger}, journal={Science}, year={1966}, volume={154 3749}, pages={673-4} }