Liver bioengineering: from the stage of liver decellularized matrix to the multiple cellular actors and bioreactor special effects.

@article{Caralt2014LiverBF,
  title={Liver bioengineering: from the stage of liver decellularized matrix to the multiple cellular actors and bioreactor special effects.},
  author={Mireia Caralt and Enrique Velasco and A. Iriarte Lanas and Pedro Viana Baptista},
  journal={Organogenesis},
  year={2014},
  volume={10 2},
  pages={
          250-9
        }
}
Liver bioengineering has been a field of intense research and popular excitement in the past decades. It experiences great interest since the introduction of whole liver acellular scaffolds generated by perfusion decellularization (1-3). Nevertheless, the different strategies developed so far have failed to generate hepatic tissue in vitro bioequivalent to native liver tissue. Even notable novel strategies that rely on iPSC-derived liver progenitor cells potential to self-organize in… CONTINUE READING
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