Liver and kidney metabolism during prolonged starvation.

  title={Liver and kidney metabolism during prolonged starvation.},
  author={Oliver E. Owen and P Felig and Alexander P. Morgan and John Wahren and George F. Cahill},
  journal={The Journal of clinical investigation},
  volume={48 3},
This study quantifies the concentrations of circulating insulin, growth hormone, glucose, free fatty acids, glycerol, beta-hydroxybutyrate, acetoacetate, and alpha amino nitrogen in 11 obese subjects during prolonged starvation. The sites and estimated rates of gluconeogenesis and ketogenesis after 5-6 wk of fasting were investigated in five of the subjects. Blood glucose and insulin concentrations fell acutely during the 1st 3 days of fasting, and alpha amino nitrogen after 17 days. The… CONTINUE READING
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