Liver after hepatocyte transplantation for liver-based metabolic disorders in children.

@article{Quaglia2008LiverAH,
  title={Liver after hepatocyte transplantation for liver-based metabolic disorders in children.},
  author={Alberto Quaglia and Sharon C. Lehec and R. D. Hughes and Ragai R. Mitry and Alexander S. Knisely and Stephen Devereaux and Julie Richards and Mohamed Rela and Nigel D. Heaton and Bernard C. Portmann and Anil Dhawan},
  journal={Cell transplantation},
  year={2008},
  volume={17 12},
  pages={1403-14}
}
There are limited data regarding donor hepatocyte engraftment into recipient liver after human hepatocyte transplantation (HHTx). We reviewed the explant livers of seven children with metabolic disorders [ornithine-transcarbamylase deficiency (one), coagulation factor VII deficiency (three), Crigler-Najjar syndrome (one), progressive familial intrahepatic cholestasis type 2 (PFIC-2) deficiency (two)] who received allograft hepatocytes by intraportal infusion with improvement in phenotype… CONTINUE READING