Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

Abstract

Liver X receptor (LXR) agonists increase both total fecal sterol excretion and macrophage-specific reverse cholesterol transport (RCT) in vivo. In this study, we assessed the effects of ABCG5/G8 deficiency as well as those of LXR agonist-induction of RCT from macrophages to feces in vivo. A [(3)H]cholesterol-labeled macrophage cell line was injected… (More)
DOI: 10.1194/jlr.M700470-JLR200

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@article{CalpeBerdiel2008LiverXR, title={Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.}, author={Laura Calpe-Berdiel and Noem{\'i} Rotllan and Catherine Fi{\'e}vet and Rosa Roig and Francisco Blanco-Vaca and Joan Carles Escol{\`a}-Gil}, journal={Journal of lipid research}, year={2008}, volume={49 9}, pages={1904-11} }