Liver Transplantation Using Donation After Cardiac Death Donors: Long‐Term Follow‐Up from a Single Center

@article{Vera2009LiverTU,
  title={Liver Transplantation Using Donation After Cardiac Death Donors: Long‐Term Follow‐Up from a Single Center},
  author={M. D. de Vera and R. Lopez-Solis and I. Dvorchik and S. Campos and W. Morris and A. Demetris and P. Fontes and J. Marsh},
  journal={American Journal of Transplantation},
  year={2009},
  volume={9}
}
There is a lack of universally accepted clinical parameters to guide the utilization of donation after cardiac death (DCD) donor livers and it is unclear as to which patients would benefit most from these organs. We reviewed our experience in 141 patients who underwent liver transplantation using DCD allografts from 1993 to 2007. Patient outcomes were analyzed in comparison to a matched cohort of 282 patients who received livers from donation after brain death (DBD) donors. Patient survival was… Expand
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219 Citations
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219 Citations

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  • Medicine
  • Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2011
TLDR
Patients undergoing DCDSLK transplantation have comparable 1‐year patient and graft survival rates and acceptable perioperative morbidity in comparison with DBD SLK transplant recipients, and the utilization of DCD organs for SLK transplants should be considered a valid approach to safely expanding the donor organ pool. Expand
Pediatric Donor to Adult Recipients in Donation After Cardiac Death Liver Transplantation: A Single-Center Experience.
TLDR
Whole liver grafts from donors younger than or equal to 13 years can potentially be used in selected size-matched (GRWR >0.7%) DCD adult recipients. Expand
Impact of donor age in liver transplantation from donation after circulatory death donors: A decade of experience at Cleveland Clinic
  • D. Firl, K. Hashimoto, +8 authors B. Eghtesad
  • Medicine
  • Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2015
The use of liver grafts from donation after circulatory death (DCD) donors remains controversial, particularly with donors of advanced age. This retrospective study investigated the impact of donor… Expand
Impact of donor age in donation after circulatory death liver transplantation: Is the cutoff “60” still of relevance?
  • A. Schlegel, I. Scalera, +5 authors P. Muiesan
  • Medicine
  • Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2018
TLDR
Older DCD donors can be successfully used for liver transplantation with good longterm outcomes when further risk factors are limited, and donor body mass index above a threshold of 25 kg/m2 significantly impacted on graft and patient survival at any donor age, whereas donor warm ischemia times were not predictive for graft loss. Expand
Liver transplantation with donation after cardiac death donors: a comprehensive update.
TLDR
By identifying certain characteristics, the transplant clinician's decision-making process can be assisted so that similar survival outcomes after OLT can be achieved with the use of hepatic DCD allografts. Expand
Livers From Pediatric Donation After Circulatory Death Donors Represent a Viable and Underutilized Source of Allograft
TLDR
It is found that pediatric DCD allografts are recovered at a significantly lower rate than from 18‐to‐40‐year‐old donors, but once recovered, these organs are transplanted at a similar rate to those from the 18-to-40-year-old donor cohort. Expand
Liver transplantation from donation after cardiac death donors: initial Belgian experience 2003–2007
  • O. Detry, V. Donckier, +11 authors R. Troisi
  • Medicine
  • Transplant international : official journal of the European Society for Organ Transplantation
  • 2010
TLDR
Results were inferior to those obtained with donation after brain death LT in this series, and prognostic criteria have to be developed to improve results of DCD‐LT. Expand
Donation after Cardiac Death Liver Transplantation: Predictors of Outcome
TLDR
Findings are useful for transplant surgeons creating DCD liver acceptance protocols and should be considered for consideration for future transplant protocols. Expand
Liver Transplantation Using Grafts From Donors After Circulatory Death: A Propensity Score–Matched Study From a Single Center
  • R. Laing, I. Scalera, +6 authors P. Muiesan
  • Medicine
  • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2016
TLDR
With appropriate recipient selection, the use of DCDs, including those deemed marginal, can be safe and can produce outcomes comparable to those seen using DBD grafts in similar recipients. Expand
The price of donation after cardiac death in liver transplantation: a prospective cost‐effectiveness study
TLDR
Reimbursement should be differentiated to better accommodate DCD transplantations, as DCD livers have more and more severe complications, more reinterventions and consequently higher costs than DBD livers. Expand
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