Liver Transplantation Using Donation After Cardiac Death Donors: Long‐Term Follow‐Up from a Single Center

@article{deVera2009LiverTU,
  title={Liver Transplantation Using Donation After Cardiac Death Donors: Long‐Term Follow‐Up from a Single Center},
  author={Michael E. de Vera and Roberto Carlos Lopez-Solis and Igor Dvorchik and Sofia Campos and William Morris and Anthony J. Demetris and Paulo Fontes and James Wallis Marsh},
  journal={American Journal of Transplantation},
  year={2009},
  volume={9}
}
There is a lack of universally accepted clinical parameters to guide the utilization of donation after cardiac death (DCD) donor livers and it is unclear as to which patients would benefit most from these organs. We reviewed our experience in 141 patients who underwent liver transplantation using DCD allografts from 1993 to 2007. Patient outcomes were analyzed in comparison to a matched cohort of 282 patients who received livers from donation after brain death (DBD) donors. Patient survival was… 

Simultaneous liver and kidney transplantation using donation after cardiac death donors: A brief report

  • J. LaMattinaJ. Mezrich D. Foley
  • Medicine
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2011
Patients undergoing DCDSLK transplantation have comparable 1‐year patient and graft survival rates and acceptable perioperative morbidity in comparison with DBD SLK transplant recipients, and the utilization of DCD organs for SLK transplants should be considered a valid approach to safely expanding the donor organ pool.

Impact of donor age in liver transplantation from donation after circulatory death donors: A decade of experience at Cleveland Clinic

  • D. FirlK. Hashimoto B. Eghtesad
  • Medicine
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2015
The use of liver grafts from donation after circulatory death (DCD) donors remains controversial, particularly with donors of advanced age. This retrospective study investigated the impact of donor

Impact of donor age in donation after circulatory death liver transplantation: Is the cutoff “60” still of relevance?

  • A. SchlegelI. Scalera P. Muiesan
  • Medicine
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2018
Older DCD donors can be successfully used for liver transplantation with good longterm outcomes when further risk factors are limited, and donor body mass index above a threshold of 25 kg/m2 significantly impacted on graft and patient survival at any donor age, whereas donor warm ischemia times were not predictive for graft loss.

Livers From Pediatric Donation After Circulatory Death Donors Represent a Viable and Underutilized Source of Allograft

It is found that pediatric DCD allografts are recovered at a significantly lower rate than from 18‐to‐40‐year‐old donors, but once recovered, these organs are transplanted at a similar rate to those from the 18-to-40-year-old donor cohort.

Liver transplantation from donation after cardiac death donors: initial Belgian experience 2003–2007

  • O. DetryV. Donckier R. Troisi
  • Medicine
    Transplant international : official journal of the European Society for Organ Transplantation
  • 2010
Results were inferior to those obtained with donation after brain death LT in this series, and prognostic criteria have to be developed to improve results of DCD‐LT.

Donation after Cardiac Death Liver Transplantation: Predictors of Outcome

Findings are useful for transplant surgeons creating DCD liver acceptance protocols and should be considered for consideration for future transplant protocols.

Liver Transplantation Using Grafts From Donors After Circulatory Death: A Propensity Score–Matched Study From a Single Center

  • R. LaingI. Scalera P. Muiesan
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2016
With appropriate recipient selection, the use of DCDs, including those deemed marginal, can be safe and can produce outcomes comparable to those seen using DBD grafts in similar recipients.

The price of donation after cardiac death in liver transplantation: a prospective cost‐effectiveness study

Reimbursement should be differentiated to better accommodate DCD transplantations, as DCD livers have more and more severe complications, more reinterventions and consequently higher costs than DBD livers.
...

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Although biliary complication rate was similar in two groups, the consequence of this complication in DCD was more severe and often led to graft loss, and the outcome of LT from DCD donors remains acceptable in this institution.

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Despite similar rates of primary nonfunction,LTx after controlled DCD resulted in worse patient and graft survival compared with LTx after DBD and increased incidence of biliary complications and hepatic artery stenosis; however, overall results of LTX after controlledDCD are encouraging; and with careful donor and recipient selection, LTx before DCD may successfully increase the donor liver pool.

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