Liver Fibrosis by Transient Elastography and Virologic Outcomes After Introduction of Tenofovir in Lamivudine-Experienced Adults With HIV and Hepatitis B Virus Coinfection in Ghana.

@article{Stockdale2015LiverFB,
  title={Liver Fibrosis by Transient Elastography and Virologic Outcomes After Introduction of Tenofovir in Lamivudine-Experienced Adults With HIV and Hepatitis B Virus Coinfection in Ghana.},
  author={Alexander J Stockdale and Richard Odame Phillips and Apostolos Beloukas and Lambert T Appiah and David R. Chadwick and Sanjay Bhagani and Laura J Bonnett and Fred Stephen Sarfo and Geoffrey Dusheiko and Anna Mar{\'i}a Geretti},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2015},
  volume={61 6},
  pages={883-91}
}
BACKGROUND Antiretroviral treatment (ART) programs in sub-Saharan Africa have for many years included lamivudine as the sole hepatitis B virus (HBV) inhibitor. Long-term outcomes and the effects of introducing tenofovir as part of ART in these populations have not been characterized. METHODS The study comprised a cross-sectional analysis of 106 human immunodeficiency virus (HIV)/HBV-coinfected subjects maintained on lamivudine, as well as a prospective analysis of 76 lamivudine-experienced… CONTINUE READING

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