Livebirth after uterus transplantation

  title={Livebirth after uterus transplantation},
  author={Mats Br{\"a}nnstr{\"o}m and Liza Johannesson and Hans Bokstr{\"o}m and Niclas Kvarnstr{\"o}m and Johan M{\"o}lne and Pernilla Dahm-K{\"a}hler and Anders Enskog and Milan Milenkovi{\'c} and Jana Ekberg and Cesar Diaz-Garcia and Markus G{\"a}bel and Ashraf Hanafy and Henrik Hagberg and Michael Olausson and Lars Nilsson},
  journal={The Lancet},

Figures from this paper

Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility

The results establish proof-of-concept for treating uterine infertility by transplantation from a deceased donor, opening a path to healthy pregnancy for all women with uterine factor infertility, without need of living donors or live donor surgery.

Introduction: Uterus transplantation.

First live birth after uterus transplantation in the Middle East

This is the first report of a healthy live birth after uterus transplantation in the MENAT region and it is hoped that this will motivate further progress and additional clinical trials in this area in the Middle East Region.

Human Uterus Transplantation: Have We Opened a Pandora’s Box?

  • G. Allahbadia
  • Medicine
    The Journal of Obstetrics and Gynecology of India
  • 2015
The only untreatable subgroup of female infertility is absolute uterine factor infertility (AUFI), which is due to congenital or surgical absence of a uterus or presence of a non-functional uterus, and human uterus transplantation is a potential future treatment of AUFI.

The Evolution of Transplantation From Saving Lives to Fertility Treatment

Uterus transplantation (UTx) aims at giving women affected by absolute uterine-factor infertility the possibility of carrying their own pregnancy and is a unique type of transplant; whose only true success is a healthy child birth.

Uterine transplantation in an era of successful childbirths from living and deceased donor uteri: Current challenges.

Uterine transplantation, after optimization of surgical methods, selection of suitable donors, standardization of immunosuppressive therapy, adjustment of assisted reproductive technologies and obstetrical proceedings might be an effective therapeutic method for women with AUFI who wish to have their own biological child.

The first live birth subsequent to uterus transplantation.

The first live birth from a transplanted uterus is a historic accomplishment and the proof of the principle that uterine transplantation can be an option for parenthood for the many women who suffer from uterine factor infertility.

Live Birth Following Uterine Transplantation From a Nulliparous Deceased Donor.

It is provided a proof of concept that nulliparous uteri may present a suitable source of uterine grafts for uterus transplantation and Stenting may serve as a feasible treatment method for vaginal anastomotic stenosis.

First live birth after uterus transplantation in the United States

  • G. TestaG. McKenna L. Johannesson
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2018
The first birth of a healthy child following uterus transplantation in the United States, from a recipient of a recipients of a uterus allograft procured from an altruistic living donor, is reported.



Clinical pregnancy after uterus transplantation.

Birth after reimplantation of a human embryo [letter]

We wish to report that 1 of our patients a 30-year-old nulliparous married woman was safely delivered by cesarean section on July 25 1978 of a normal healthy infant girl weighing 2700 g. The patient

Transplantation of the human uterus

  • W. FageehH. RaffaH. JabbadA. Marzouki
  • Medicine
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • 2002

Preclinical report on allogeneic uterus transplantation in non-human primates.

The findings suggest that allogeneic UTx in primate species is feasible but continued work on this issue is needed, and further research is needed to optimize immunosuppression protocols in order to avoid uterine rejection.

Experimental uterus transplantation.

Much research on UTx has been performed in appropriate animal models and it is predicted that the research will soon reach a stage that could merit introduction of human UTx as an experimental procedure.

Uterine transplantation research: laboratory protocols for clinical application.

The aim of this review is to summarize the state-of the-art methods that are used in clinical organ transplantation today, as well as the major findings of recent experimental uterus transplantation

Pregnancy in the sixth decade of life: obstetric outcomes in women of advanced reproductive age.

CONTEXT As a result of oocyte donation, women in their sixth decade of life are now able to conceive and carry pregnancies to term. However, little is known about pregnancy outcomes in this