Live mammalian cell arrays

Abstract

High-content assays have the potential to drastically increase throughput in cell biology and drug discovery, but handling and culturing large libraries of cells such as primary tumor or cancer cell lines requires expensive, dedicated robotic equipment. We developed a simple yet powerful method that uses contact spotting to generate high-density nanowell arrays of live mammalian cells for the culture and interrogation of cell libraries.

DOI: 10.1038/nmeth.2473

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@article{Woodruff2013LiveMC, title={Live mammalian cell arrays}, author={Kristina Woodruff and Luis Fidalgo and Samy Gobaa and Matthias P Lutolf and Sebastian Maerkl}, journal={Nature Methods}, year={2013}, volume={10}, pages={550-552} }