Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis

@inproceedings{Xu2013LiveIA,
  title={Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis},
  author={Yangqing Xu and Junying Yuan and Marta M. Lipinski},
  booktitle={Autophagy},
  year={2013}
}
Autophagy is induced by many cytotoxic stimuli but it is often unclear whether, under specific conditions, autophagy plays a prosurvival or a prodeath role. To answer this critical question we developed a novel methodology that employs automated live microscopy and image analysis to measure autophagy and apoptosis simultaneously in single cells. We used… CONTINUE READING