Live attenuated influenza vaccine for children with egg allergy

  title={Live attenuated influenza vaccine for children with egg allergy},
  author={Matthew Greenhawt},
  journal={BMJ : British Medical Journal},
  • M. Greenhawt
  • Published 9 December 2015
  • Medicine
  • BMJ : British Medical Journal
Policies should change to allow vaccination, after compelling new evidence of safety 
4 Citations

Live Attenuated Influenza Vaccine Is Safe in Egg-Allergic Patients

The majority of influenza vaccines available are grown in hens' eggs and may contain trace amounts of egg protein, but there are also vaccines that do not contain egg protein.

Challenges in the development of egg-independent vaccines for influenza

Changes in vaccine production methods are not merely ‘technical changes’; rather, they involve various aspects that slow down the authorization of new influenza vaccines and make the complete replacement of egg-based production unlikely in the near future.

The baculovirus expression vector system: a modern technology for the future of influenza vaccine manufacturing

This review focuses on the recombinant DNA technology using baculovirus expression vector system a modern method of manufacturing licensed influenza vaccines, which offers great advantages over egg- and cell-based influenza vaccine production.



Influenza immunization in egg allergy: an update for the 2011–2012 season

An updated guideline for immunization during the 2011–2012 flu season is provided and recent experience suggests that some vaccines with very low ovalbumin concentrations may be safe for use in primary care in carefully assessed low‐risk individuals.

Safety of live attenuated influenza vaccine in atopic children with egg allergy

Safe administration of the measles vaccine to children allergic to eggs.

The MMR vaccine can be safely administered in a single dose to children with allergy to eggs, even those with severe hypersensitivity, and none had an immediate or delayed adverse reaction.

Safe administration of the seasonal trivalent influenza vaccine to children with severe egg allergy.

  • M. GreenhawtJ. Spergel G. Sanders
  • Medicine
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 2012

Recommendations for using MMR vaccine in children allergic to eggs

The evidence for egg as the agent responsible for allergic reactions to MMR or measles vaccine is reviewed and recommended based on the evidence and the arguments presented also apply to the single mumps vaccine and all other vaccines derived from egg.

Safety of live attenuated influenza vaccine in young people with egg allergy: multicentre prospective cohort study

LAIV is associated with a low risk of systemic allergic reactions in young people with egg allergy and seems to be well tolerated in those with well controlled asthma or recurrent wheeze.

Adverse reactions to vaccines practice parameter 2012 update.

Prevention and Control of Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2015–16 Influenza Season

This report updates the 2014 recommendations of the Advisory Committee on Immunization Practices regarding the use of seasonal influenza vaccines, including removal of the 2014-15 preferential recommendation for LAIV for healthy children aged 2 through 8 years.

Cost-effectiveness analysis of intranasal live attenuated vaccine (LAIV) versus injectable inactivated influenza vaccine (TIV) for Canadian children and adolescents

LAIV reduces the burden of influenza in children and adolescents and vaccinating children with LAIV, rather than TIV, is the dominant strategy from both a societal perspective and a Ministry of Health perspective.

EAACI Food Allergy and Anaphylaxis Guidelines

  • Medicine
  • 2013
This guideline will examine the possible applications of these instruments and provide advice to clinicians and investigators on their proper use and the interpretation of results, and will focus on instruments designed to measure HRQL in a quantitative and disease-specific fashion.