Live attenuated SIV vaccines are not effective in a postexposure vaccination model.

@article{Linhart1997LiveAS,
  title={Live attenuated SIV vaccines are not effective in a postexposure vaccination model.},
  author={Heinz G. Linhart and B R Gundlach and Sieghart Sopper and Ulf Dittmer and Kerstin M{\"a}tz-Rensing and Evelyn Meyer Kuhn and Jo{\"e}l M{\"u}ller and Gerhard Hunsmann and Christiane Stahl-Hennig and Klaus Uberla},
  journal={AIDS research and human retroviruses},
  year={1997},
  volume={13 7},
  pages={
          593-9
        }
}
Live attenuated simian immunodeficiency virus (SIV) vaccines, like nef deletion mutants, have been the most effective vaccines tested in the SIV/macaque model so far. The efficacy of live attenuated SIV vaccines in therapeutic vaccination and postexposure prophylaxis has not been determined. Inoculation of macaques with a pathogenic challenge virus and an attenuated SIV vaccine at the same time mimics postexposure vaccination, whereby vaccination with the attenuated virus is performed as… CONTINUE READING