Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

Abstract

Stem cells reside in a specialized, regulatory environment termed the niche that dictates how they generate, maintain and repair tissues. We have previously documented that transplanted haematopoietic stem and progenitor cell populations localize to subdomains of bone-marrow microvessels where the chemokine CXCL12 is particularly abundant. Using a… (More)
DOI: 10.1038/nature07434

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