Live Imaging of Whole Mouse Embryos during Gastrulation: Migration Analyses of Epiblast and Mesodermal Cells

@inproceedings{Ichikawa2013LiveIO,
  title={Live Imaging of Whole Mouse Embryos during Gastrulation: Migration Analyses of Epiblast and Mesodermal Cells},
  author={Takehiko Ichikawa and Kenichi Nakazato and Philipp J. Keller and Hiroko Kajiura-Kobayashi and Ernst H. K. Stelzer and Atsushi Mochizuki and Shigenori Nonaka},
  booktitle={PloS one},
  year={2013}
}
During gastrulation in the mouse embryo, dynamic cell movements including epiblast invagination and mesodermal layer expansion lead to the establishment of the three-layered body plan. The precise details of these movements, however, are sometimes elusive, because of the limitations in live imaging. To overcome this problem, we developed techniques to enable observation of living mouse embryos with digital scanned light sheet microscope (DSLM). The achieved deep and high time-resolution images… CONTINUE READING
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