Live Candida albicans suppresses production of reactive oxygen species in phagocytes.

@article{Wellington2009LiveCA,
  title={Live Candida albicans suppresses production of reactive oxygen species in phagocytes.},
  author={Melanie A Wellington and Kristy Dolan and Damian J Krysan},
  journal={Infection and immunity},
  year={2009},
  volume={77 1},
  pages={405-13}
}
Production of reactive oxygen species (ROS) is an important aspect of phagocyte-mediated host responses. Since phagocytes play a crucial role in the host response to Candida albicans, we examined the ability of Candida to modulate phagocyte ROS production. ROS production was measured in the murine macrophage cell line J774 and in primary phagocytes using luminol-enhanced chemiluminescence. J774 cells, murine polymorphonuclear leukocytes (PMN), human monocytes, and human PMN treated with live C… CONTINUE READING

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