Live Analysis of Endodermal Layer Formation Identifies Random Walk as a Novel Gastrulation Movement

@article{Pzeron2008LiveAO,
  title={Live Analysis of Endodermal Layer Formation Identifies Random Walk as a Novel Gastrulation Movement},
  author={Guillaume P{\'e}zeron and Philippe Mourrain and S{\'e}bastien Courty and Julien Ghislain and Thomas Becker and Fr{\'e}d{\'e}ric Marc Rosa and Nicolas B David},
  journal={Current Biology},
  year={2008},
  volume={18},
  pages={276-281}
}
During gastrulation, dramatic movements rearrange cells into three germ layers expanded over the entire embryo [1-3]. In fish, both endoderm and mesoderm are specified as a belt at the embryo margin. Mesodermal layer expansion is achieved through the combination of two directed migrations. The outer ring of precursors moves toward the vegetal pole and continuously seeds mesodermal cells inside the embryo, which then reverse their movement in the direction of the animal pole [3-6]. Unlike… CONTINUE READING