Littoral cell angioma. A novel splenic vascular lesion demonstrating histiocytic differentiation.

@article{Falk1991LittoralCA,
  title={Littoral cell angioma. A novel splenic vascular lesion demonstrating histiocytic differentiation.},
  author={Sandor Falk and Hans Jochen Stutte and Glauco Frizzera},
  journal={The American journal of surgical pathology},
  year={1991},
  volume={15 11},
  pages={
          1023-33
        }
}
Seventeen cases of a novel type of vascular tumor of the spleen are described. The lesions, whose size ranges from minute foci to large nodules almost completely replacing the splenic tissue, are composed of anastomosing vascular channels resembling splenic sinus and have irregular lumina, often featuring papillary projections and cyst-like spaces; they are lined by tall endothelial cells that slough off into the vascular lumina and show hemophagocytosis. Atypical cells are absent and mitotic… CONTINUE READING
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