Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed.

@article{Bedlack2008LithiumMS,
  title={Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed.},
  author={Richard S. Bedlack and Nicholas J. Maragakis and Terry D. Heiman-Patterson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 16},
  pages={E17; author reply E18}
}
To the Editor: In the February 12, 2008 edition of PNAS, Fornai et al. (1) suggest that lithium slows human ALS progression. We have several questions about their study. Was this trial registered before enrollment, as required by the International Committee of Medical Journal Editors (2)? If not, why? How were participants selected? What were the inclusion/exclusion criteria? How many were screened to accrue 44 participants? Most ALS trials employ a 1:1 randomization ratio or one that places… CONTINUE READING

From This Paper

Topics from this paper.
7 Citations
0 References
Similar Papers

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…