Lithium intoxication. (Report of 23 cases and review of 100 cases from the literature).

@article{Hansen1978LithiumI,
  title={Lithium intoxication. (Report of 23 cases and review of 100 cases from the literature).},
  author={Hans Erik Hansen and Amdi Amdisen},
  journal={The Quarterly journal of medicine},
  year={1978},
  volume={47 186},
  pages={123-44}
}
Twenty-three patients were studied, 21 of whom developed intoxication during maintenance therapy with a lithium dosage which had been unchanged for months to years. Toxic effects on brain, heart and kidneys were found and the severity of lithium intoxication seemed to depend on at least three factors: the height of the serum lithium concentration (SLi), the duration of lithium intoxication and individual tolerance. Disorders of water and electrolyte metabolism preceded lithium intoxication in… CONTINUE READING
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