Lithium induces c-Ret expression in mouse inner medullary collecting duct cells.

@article{Kojima2011LithiumIC,
  title={Lithium induces c-Ret expression in mouse inner medullary collecting duct cells.},
  author={Nobuhiko Kojima and Hiroshi Saito and Masaki Nishikawa and Shunsuke Yuri and Oak Don Jo and Phuong-Chi Pham and Naomi Yanagawa and Norimoto Yanagawa},
  journal={Cellular signalling},
  year={2011},
  volume={23 2},
  pages={371-9}
}
We found in our present study that lithium (Li(+)) induced the expression of endogenous c-Ret, a tyrosine kinase receptor, in murine inner medullary collecting duct (mIMCD-3) cells. Delineation of the promoter region required for the effect of Li(+) identified a positive regulatory element within 180bp upstream of the transcription initiation site. This region contained three putative GC-rich Sp1 binding sites found to be essential for c-Ret induction by Li(+). The effect of Li(+) was mediated… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Chem

  • L. Meijer, A. L. Skaltsounis, +13 authors P. Greengard
  • Biol. 10
  • 2003
Highly Influential
6 Excerpts

Trends Genet

  • S. Manie, M. Santoro, A. Fusco, M. Billaud
  • 17
  • 2001
Highly Influential
3 Excerpts

H

  • J. G. Pichel, L. Shen, +8 authors H. Sariola
  • Westphal, Nature 382
  • 1996
Highly Influential
13 Excerpts

K

  • R. R. Rao, Q. Li
  • Odunsi, P.A. Shrikant, Immunity 32
  • 2010

Br

  • G. V. Rayasam, V. K. Tulasi, R. Sodhi, J. A. Davis, A. Ray
  • J. Pharmacol. 156
  • 2009
2 Excerpts

Pediatr

  • D. Bridgewater, N. D. Rosenblum
  • Nephrology (Berlin Ger.) 24
  • 2009
1 Excerpt

Soc

  • W. Lieberthal, J. S. Levine, J. Am
  • Nephrol. 20
  • 2009
1 Excerpt

Surg

  • T. Y. Leon, E. S. Ngan, +5 authors J. Pediatr
  • 44
  • 2009
1 Excerpt

Dev

  • T. D. Marose, C. E. Merkel, A. P. McMahon, T. J. Carroll
  • Biol. 314
  • 2008

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