Lithium for older adults with bipolar disorder: Should it still be considered a first-line agent?

@article{Shulman2010LithiumFO,
  title={Lithium for older adults with bipolar disorder: Should it still be considered a first-line agent?},
  author={Kenneth I Shulman},
  journal={Drugs & aging},
  year={2010},
  volume={27 8},
  pages={607-15}
}
The use of lithium carbonate for the treatment of bipolar disorder in older adults is decreasing at a significant rate. This change in prescription pattern is occurring at a time when all evidence-based treatment guidelines and systematic reviews still recommend lithium as a first-line treatment for bipolar disorder. Despite having the strongest evidence base for effectiveness, lithium does pose significant concerns in the older population, including the risk of drug interactions that cause… CONTINUE READING

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