Lithium for maintenance treatment of mood disorders.

  title={Lithium for maintenance treatment of mood disorders.},
  author={Sally Burgess and John Geddes and Keith Hawton and Elissa Townsend and Kay R. Jamison and Graham Goodwin},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Mood disorders are common, disabling and tend to be recurrent. They carry a high risk of suicide. Maintenance treatment, aimed at the prevention of relapse, is therefore of vital importance. Lithium has been used for some years as the mainstay of maintenance treatment in bipolar affective disorder, and to a lesser extent in unipolar disorder. However, the efficacy and effectiveness of prophylactic lithium therapy has been disputed. Low suicide rates in lithium-treated patients have… CONTINUE READING


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