Lithium evokes expression of vegetal-specific molecules in the animal blastomeres of sea urchin embryos.

@article{Livingston1989LithiumEE,
  title={Lithium evokes expression of vegetal-specific molecules in the animal blastomeres of sea urchin embryos.},
  author={Brian T. Livingston and Fred H Wilt},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 10},
  pages={3669-73}
}
The mechanism of determination of early embryonic cells has been investigated using sea urchin embryos. An efficacious method of isolating blastomere pairs from the animal or vegetal half of sea urchin embryos was developed. The overt differentiation of separated animal and vegetal blastomere pairs resembles that of separated animal and vegetal hemispheres isolated by manual dissection. Treatment of animal blastomeres with LiCl caused them to display a morphology resembling that of isolated… CONTINUE READING

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