Lithium citrate for Canavan disease.

@article{Janson2005LithiumCF,
  title={Lithium citrate for Canavan disease.},
  author={Christopher G. Janson and Mitra Assadi and J. Sullivan Francis and Larissa T. Bilaniuk and David Shera and Paola A. Leone},
  journal={Pediatric neurology},
  year={2005},
  volume={33 4},
  pages={
          235-43
        }
}
Current evidence suggests that the effects of lithium on metabolic and signaling pathways in the brain may vary depending on the specific clinical condition or disease model. For example, lithium increases levels of cerebral N-acetyl aspartate in patients with bipolar disorder but does not appear to affect N-acetyl aspartate levels in normal human subjects. Conversely, lithium significantly decreases whole-brain levels of N-acetyl aspartate in a rat genetic model of Canavan disease in which… CONTINUE READING
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