Lithium butylchalcogenolate induced Michael-aldol tandem sequence: easy and rapid access to highly functionalized organochalcogenides and unsaturated compounds

@inproceedings{Keppler2009LithiumBI,
  title={Lithium butylchalcogenolate induced Michael-aldol tandem sequence: easy and rapid access to highly functionalized organochalcogenides and unsaturated compounds},
  author={Artur Franz Keppler and Rog{\'e}rio A. Gariani and Danilo G. Lopes and Jo{\~a}o Valdir Comasseto},
  year={2009}
}
Abstract Lithium n butylchalcogenolates are generated in situ by reacting the elements (S, Se, and Te) with n butyllithium at 0 °C. Reaction of the lithium alkylchalcogenolates with activated alkenes and aldehydes gives the corresponding aldol adducts. The selenium-containing products give Morita–Baylis–Hillman adducts after the oxidation/elimination of the selenoxide. The whole sequence can be performed in a one-pot procedure.