Lithium augmentation therapy in tricyclic-resistant depression. A controlled trial using lithium in low and normal doses.

@article{Stein1993LithiumAT,
  title={Lithium augmentation therapy in tricyclic-resistant depression. A controlled trial using lithium in low and normal doses.},
  author={G{\"u}nter Stein and Morris Bernadt},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1993},
  volume={162},
  pages={
          634-40
        }
}
Thirty-four patients with tricyclic-resistant depressive illness took part in a nine-week, double-blind, placebo-controlled trial of lithium augmentation. In addition to the maximum tolerated doses of their tricyclic antidepressant, the experimental group (n = 16) received 250 mg lithium daily for three weeks, followed by 750 mg lithium daily for six weeks, while the controls (n = 18) received placebo for three weeks followed by three weeks each of 250 mg lithium daily and 750 mg lithium daily… CONTINUE READING

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