Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder

@inproceedings{McLean2018LithiumassociatedTR,
  title={Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder},
  author={Charlee K. McLean and Soumya Narayan and Sandra Y. Lin and Narayan Rai and Youjin Chung and M Hipolito and Nicola Cascella and John J I Nurnberger and Koko Ishizuka and Akira S. Sawa and Evaristus A. Nwulia},
  booktitle={Translational Psychiatry},
  year={2018}
}
There is growing evidence that lithium used in the treatment of bipolar disorder (BD) affects molecular targets that are involved in neuronal growth, survival, and maturation, but it remains unclear if neuronal alterations in any of these molecules predict specific symptom changes in BD patients undergoing lithium monotherapy. The goals of this study were… CONTINUE READING