Lithium and the structure of exploratory behavior in the rat.


1. Adult male Sprague Dawley rats were given lithium as a dietary supplement, or a control diet. 2. A single seven hour test of exploratory behavior was carried out after one week of chronic drug exposure . 3. The structure of exploration was significantly altered by the diet, with experimental animals exploring less intensely and with increased spacing of activity episodes. 4. These findings may represent a useful preclinical analog of some typically observed therapeutic effects of lithium.

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@article{Katz1980LithiumAT, title={Lithium and the structure of exploratory behavior in the rat.}, author={Richard J. Katz}, journal={Progress in neuro-psychopharmacology}, year={1980}, volume={4 1}, pages={37-41} }