Lithium ameliorates rat spinal cord injury by suppressing glycogen synthase kinase-3β and activating heme oxygenase-1

@inproceedings{Kim2017LithiumAR,
  title={Lithium ameliorates rat spinal cord injury by suppressing glycogen synthase kinase-3β and activating heme oxygenase-1},
  author={Yonghoon Kim and Jeongtae Kim and Meejung Ahn and Taekyun Shin},
  booktitle={Anatomy & cell biology},
  year={2017}
}
Glycogen synthase kinase (GSK)-3β and related enzymes are associated with various forms of neuroinflammation, including spinal cord injury (SCI). Our aim was to evaluate whether lithium, a non-selective inhibitor of GSK-3β, ameliorated SCI progression, and also to analyze whether lithium affected the expression levels of two representative GSK-3β-associated… CONTINUE READING