Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury.

@article{Yu2012LithiumAN,
  title={Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury.},
  author={Fengshan Yu and Zhifei Wang and Flaubert Tchantchou and Chi-Tso Chiu and Yu-min Zhang and D. -M. Chuang},
  journal={Journal of neurotrauma},
  year={2012},
  volume={29 2},
  pages={362-74}
}
Although traumatic brain injury (TBI) is recognized as one of the leading causes of death from trauma to the central nervous system (CNS), no known treatment effectively mitigates its effects. Lithium, a primary drug for the treatment of bipolar disorder, has been known to have neuroprotective effects in various neurodegenerative conditions such as stroke. Until this study, however, it has not been investigated as a post-insult treatment for TBI. To evaluate whether lithium could have… CONTINUE READING
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