Lithium: Effect on [3H]spiperone binding, ionic content, and amino acid levels in the brain of rats

@article{BanaySchwartz1982LithiumEO,
  title={Lithium: Effect on [3H]spiperone binding, ionic content, and amino acid levels in the brain of rats},
  author={Miriam Banay-Schwartz and Isabel J. Wajda and Isaac Manigault and Terri DeGuzman and Abel Lajtha},
  journal={Neurochemical Research},
  year={1982},
  volume={7},
  pages={179-189}
}
After prolonged treatment of rats with lithium (pellets, 0.21% lithium carbonate, or 0.5 mg/ml lithium chloride in drinking water) for three months, the level of lithium in plasma was 0.87 meq/liter; in several brain regions, between 1.06–1.39 μeq/g wet weight. The content of sodium and potassium in the plasma was normal. The level of potassium in the brain regions tested increased by 13–30% and that of sodium by about 10%. Glycine levels increased significantly in all the regions (cerebral… CONTINUE READING