We read with great interest the Editorial on 123-iodomethyl tyrosine (IMT) single-photon emission tomography . However, an Editorial should cover the entire history of this radiopharmaceutical . In January 1989, we published initial results using IMT in brain tumours . However, the first paper on IMT in animal experiments (pancreas of mice) had already been published by Tisljar et al. from Jülich in 1979 . Its use for imaging of the pancreas in humans had been proposed by Kloster et al. in 1982 . Again, the Jülich group  used IMT as a potential melanoma-seeking compound, after this agent had been proposed for adrenal medulla and melanoma imaging in 1979. Bockslaff et al. were the first to publish clinical results in humans using IMT for noninvasive detection of intra-ocular melanoma . I strongly feel that this update of IMT imaging is appropriate to complete Dr. Matheja’s work. Especially our younger readers might be pleased to have full knowledge of the development of IMT.