Literature review and practical aspects on the management of oxaliplatin-associated toxicity.

@article{Hoff2012LiteratureRA,
  title={Literature review and practical aspects on the management of oxaliplatin-associated toxicity.},
  author={Paulo Marcelo Gehm Hoff and Everardo Delforge Saad and Frederico G. I. da Costa and Anelisa Kruschewsky Coutinho and Ricardo Caponero and Gabriel Prolla and Rene Claudio Gansl},
  journal={Clinical colorectal cancer},
  year={2012},
  volume={11 2},
  pages={93-100}
}
Colorectal cancer is currently a public health priority because it is the second leading cause of cancer deaths in Western countries. Combination regimes of oxaliplatin and infusional fluorouracil/leucovorin or capecitabine have emerged as important options in the palliative and adjuvant treatment of colorectal cancer. Although better tolerated than cisplatin, oxaliplatin displays a characteristic profile of adverse events whose recognition and management are essential for physicians who treat… CONTINUE READING