Literature Review: Update on Amphetamine Neurotoxicity and Its Relevance to the Treatment of ADHD

  title={Literature Review: Update on Amphetamine Neurotoxicity and Its Relevance to the Treatment of ADHD},
  author={C. Advokat},
  journal={Journal of Attention Disorders},
  pages={16 - 8}
  • C. Advokat
  • Published 2007
  • Psychology, Medicine
  • Journal of Attention Disorders
Objective: A review of amphetamine treatment for attention-deficit/hyperactivity disorder (ADHD) was conducted, to obtain information on the long-term neurological consequences of this therapy. Method: Several databases were accessed for research articles on the effects of amphetamine in the brain of laboratory animals and ADHD diagnosed individuals. Results: In early studies, high doses of amphetamine, comparable to amounts used by addicts, were shown to damage dopaminergic pathways. More… Expand
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