Listeria monocytogenes infection in caspase-11-deficient mice.


Caspase-11 (Cas11) is a cysteine protease involved in programmed cell death and cytokine maturation. Through activation of Cas1 (interleukin-1beta [IL-1beta]-converting enzyme), Cas11 is directly involved in the maturation of IL-1beta and IL-18. Apoptosis is mediated through Cas3. Given the role of apoptosis and cytokine signaling during the innate immune… (More)


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@article{Mueller2002ListeriaMI, title={Listeria monocytogenes infection in caspase-11-deficient mice.}, author={Nicolas J Mueller and R. A. Wilkinson and Jay A Fishman}, journal={Infection and immunity}, year={2002}, volume={70 5}, pages={2657-64} }