Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection.

@article{Leito2014ListeriaMI,
  title={Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection.},
  author={Elsa Leit{\~a}o and Ana Catarina Costa and Claudia Brito and Lionel Costa and Rita Pombinho and Didier Cabanes and Sandra Sousa},
  journal={Cell cycle},
  year={2014},
  volume={13 6},
  pages={928-40}
}
Listeria monocytogenes (Lm) is a human intracellular pathogen widely used to uncover the mechanisms evolved by pathogens to establish infection. However, its capacity to perturb the host cell cycle was never reported. We show that Lm infection affects the host cell cycle progression, increasing its overall duration but allowing consecutive rounds of division. A complete Lm infectious cycle induces a S-phase delay accompanied by a slower rate of DNA synthesis and increased levels of host DNA… CONTINUE READING
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