Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study

@inproceedings{Rizzo2014LiraglutideDC,
  title={Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study},
  author={Manfredi Rizzo and Manisha S. Chandalia and Angelo Maria Patti and Vittoria Di Bartolo and Ali A. Rizvi and Giuseppe Montalto and Nicola I Abate},
  booktitle={Cardiovascular diabetology},
  year={2014}
}
BACKGROUND Liraglutide, a long-acting glucagon-like peptide-1 (GLP-1) analog, has several non- glycemic properties, but its effect on carotid intima-media thickness (IMT), a recognized marker of subclinical atherosclerosis, is still unknown. METHODS A prospective study of 8 months duration in 64 patients with type-2 diabetes and no prior history of coronary artery disease evaluated whether adding liraglutide to metformin affects carotid IMT, measured by color doppler ultrasound. RESULTS… CONTINUE READING