Liquid chromatography in pharmaceutical analysis VII: determination of dantrolene sodium in biological fluids.

Abstract

Dantrolene sodium can be determined in plasma and urine samples by high-pressure liquid chromatography without interference from its two major metabolites, the hydroxy and acetamido compounds. The minimum detectability of the drug using this procedure is 8 ng. The complete assay including extraction, evaporation, and separation steps can be performed in… (More)

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@article{Saxena1977LiquidCI, title={Liquid chromatography in pharmaceutical analysis VII: determination of dantrolene sodium in biological fluids.}, author={Sanjaya Saxena and Irwin L. Honigberg and J. T. Stewart and J J Vallner}, journal={Journal of pharmaceutical sciences}, year={1977}, volume={66 5}, pages={751-3} }