Liquid chromatography coupled to quadruple time-of-flight tandem mass spectrometry for microcystin analysis in freshwaters: method performances and characterisation of a novel variant of microcystin-RR.

@article{Ferranti2009LiquidCC,
  title={Liquid chromatography coupled to quadruple time-of-flight tandem mass spectrometry for microcystin analysis in freshwaters: method performances and characterisation of a novel variant of microcystin-RR.},
  author={Pasquale Ferranti and Serena Fabbrocino and Antonella Nasi and Simonetta Caira and Milena Bruno and Luigi Serpe and Pasquale Gallo},
  journal={Rapid communications in mass spectrometry : RCM},
  year={2009},
  volume={23 9},
  pages={1328-36}
}
Cyanobacteria, also called blue-green algae, occur worldwide within water blooms in eutrophic lakes and drinking water reservoirs, producing several biotoxins (cyanotoxins). Among these, microcystins (MCs) are a group of cyclic heptapeptides showing potent hepatotoxicity and activity as tumour promoters. So far, at least 89 MCs from different cyanobacteria genera have been characterised. Herein, ion trap, matrix-assisted laser desorption/ionisation time-of-flight (MALDI-ToF) and quadruple time… CONTINUE READING
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