Liquid chromatographic determination of methyldopa and methyldopa-thiazide combinations in tablets: collaborative study.

@article{Ting1984LiquidCD,
  title={Liquid chromatographic determination of methyldopa and methyldopa-thiazide combinations in tablets: collaborative study.},
  author={Shou-Tian Ting},
  journal={Journal - Association of Official Analytical Chemists},
  year={1984},
  volume={67 6},
  pages={1118-20}
}
  • Shou-Tian Ting
  • Published 1984 in
    Journal - Association of Official Analytical…
A reverse phase liquid chromatographic method for the determination of methyldopa, methyldopa-hydrochlorothiazide, and methyldopachlorothiazide in tablets was collaboratively studied by 8 laboratories. Each collaborator received 20 samples that included drug substance, synthetic and commercial tablet compositions. The overall repeatability and reproducibility standard deviations for commercial tablets were 1.11 and 1.75% for methyldopa, 0.96 and 1.62% for chlorothiazide, and 1.21 and 2.15% for… CONTINUE READING