Liquid chromatographic analysis of brain homogenates and microdialysates for the quantification of L-[beta-11C]DOPA and its metabolites for the validation of positron emission tomography studies.

@article{Lindner1995LiquidCA,
  title={Liquid chromatographic analysis of brain homogenates and microdialysates for the quantification of L-[beta-11C]DOPA and its metabolites for the validation of positron emission tomography studies.},
  author={K. J. Lindner and Per Hartvig and Joakim Tedroff and A Ljungstr{\"o}m and Peter Bjurling and Bengt L{\aa}ngstr{\"o}m},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={1995},
  volume={13 4-5},
  pages={361-7}
}
The clinical use of positron emission tomography, PET, with selected radiolabelled tracer molecules visualizing and quantitating physiological processes in the tissue relies in many situations on compartmental models for the interpretation of the radiosignal. Validation of such models must, therefore, include chromatographic analysis of the radioactivity composition of the signal. Rapid and sensitive liquid chromatographic methods amenable for automation for the analysis of [11C] labelled L… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

Similar Papers

Loading similar papers…