Liquid biopsies come of age: towards implementation of circulating tumour DNA

@article{Wan2017LiquidBC,
  title={Liquid biopsies come of age: towards implementation of circulating tumour DNA},
  author={Jonathan C M Wan and Charles E Massie and Javier Garcia-Corbacho and Florent Mouliere and James D. Brenton and Carlos Caldas and Simon C Pacey and Richard D. Baird and Nitzan Rosenfeld},
  journal={Nature Reviews Cancer},
  year={2017},
  volume={17},
  pages={223-238}
}
Improvements in genomic and molecular methods are expanding the range of potential applications for circulating tumour DNA (ctDNA), both in a research setting and as a 'liquid biopsy' for cancer management. Proof-of-principle studies have demonstrated the translational potential of ctDNA for prognostication, molecular profiling and monitoring. The field is now in an exciting transitional period in which ctDNA analysis is beginning to be applied clinically, although there is still much to learn… 
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